Kumxholo wenjongo "yekhabhoni ezimbini" kunye nokuguqulwa kohlaza kushishino lwezilwanyana zehlabathi, itekhnoloji encinci ye-peptide trace element ibe sisixhobo esiphambili sokusombulula ukuchasana okumbini "kokuphucula umgangatho kunye nokusebenza kakuhle" kunye "nokhuseleko lwendalo" kwishishini kunye neempawu zayo ezisebenzayo zokufunxa kunye nokunciphisa ukukhutshwa. Ngokuphunyezwa kwe-EU "Co-additive Regulation (2024 / EC)" kunye nokuthandwa kweteknoloji ye-blockchain, intsimi ye-organic micro-minerals ifumana utshintsho olunzulu olusuka kwi-empirical formulation ukuya kwiimodeli zesayensi, kunye nolawulo olubanzi ukuya ekulandeleni ngokupheleleyo. Eli nqaku lihlalutya ngokucwangcisiweyo ixabiso lesicelo sobuchwepheshe be-peptide encinci, idibanisa isikhokelo somgaqo-nkqubo wokufuywa kwezilwanyana, utshintsho kwimfuno yemarike, ukuphumelela kweteknoloji yeepeptide ezincinci, kunye neemfuno zomgangatho, kunye nezinye iindlela zokusika, kwaye iphakamisa indlela yokuguqula uhlaza ekufuyweni kwezilwanyana kwi-2025.
1. Iindlela zomgaqo-nkqubo
I-1) I-EU iphumeze ngokusemthethweni uMthetho wokuNcitshiswa kwemfuyo ngoJanuwari 2025, ifuna ukunciphisa i-30% kwiintsalela zetsimbi enzima kwisondlo, kunye nokukhawulezisa ukuguqulwa kweshishini kwizinto eziphilayo. Umthetho we-Green Feed Act ka-2025 ufuna ngokucacileyo ukuba ukusetyenziswa kwezinto ezingenayo i-inorganic trace (ezifana ne-zinc sulfate kunye ne-copper sulfate) kwisondlo kuncitshiswe ngo-50% ngo-2030, kwaye iimveliso ze-organic chelated zikhuthazwa njengento ephambili.
2) UMphathiswa wezoLimo kunye neMicimbi yaseMaphandleni waseTshayina ukhuphe i-“Green Access Catalog for Feed Additives”, kunye neemveliso ezincinci ze-peptide chelated zidweliswe "njengezinye iindlela ezicetyiswayo" okokuqala.
3) I-Asia-mpuma ye-Asia: Amazwe amaninzi asungule ngokudibeneyo "iSicwangciso sokuLima i-Antibiotic yeZero" ukukhuthaza izinto ezilandelwayo ukusuka "kwizongezelelo zesondlo" ukuya "kulawulo olusebenzayo" (njengokuchasana noxinzelelo kunye nokuphucula umzimba).
2. Utshintsho kwimfuno yemarike
Ukunyuka kwemfuno yabathengi "yenyama enentsalela ye-antibiotics" iqhube imfuno yezinto zokulandelela ezihambelana nokusingqongileyo ezinamazinga aphezulu okufunxa kwicala lokufama. Ngokwezibalo zemizi-mveliso, ubungakanani bentengiso yehlabathi jikelele yezinto ezincinci zepeptide chelated trace zonyuke ngama-42% unyaka nonyaka kwi-Q1 2025.
Ngenxa yemozulu embi kakhulu eNyakatho Melika nakwi-Asia-mpuma ye-Asia, iifama zihlawula ingqwalasela engakumbi indima yezinto ezilandelwayo ekuchaseni uxinzelelo kunye nokuphucula ukukhuseleka kwezilwanyana.
3. Impumelelo yetekhnoloji: olona khuphiswano lweemveliso ezincinci ze-peptide chelated trace
1) Ukufumaneka kwe-bioavailability okusebenzayo, ukwaphula ibhotile yokufunxa ngokwesiko
Iipeptides ezincinci ze-chelate zilandelelanisa izinto ngokusonga i-ion zetsimbi ngamatyathanga e-peptide ukwenza ii-complexes ezizinzileyo, ezifunxwa ngenkuthalo ngenkqubo yothutho ye-peptide yamathumbu (efana ne-PepT1), ukuphepha ukonakala kwe-asidi ye-gastric kunye ne-ion antagonism, kunye ne-bioavailability yazo ngamaxesha angama-2-3 aphezulu kuneetyuwa ezingaphili.
2) I-synergy esebenzayo ukuphucula ukusebenza kwemveliso kwimilinganiselo emininzi
Izinto ezincinci ze-peptide trace zilawula i-intestinal flora (ibhaktheriya ye-lactic acid ikhula ngamaxesha angama-20-40), ukuphucula ukuphuhliswa kwamalungu omzimba (i-antibody titer inyuka ngamaxesha angama-1.5), kunye nokwandisa ukufunxa izondlo (umlinganiselo wokutya ukuya kwinyama ufikelela kwi-2.35: 1), ngaloo ndlela iphucula ukusebenza kwemveliso kwimilinganiselo emininzi (+ 48%) kunye nemveliso ye-egg.
3) Ukuzinza okuqinileyo, ukukhusela ngokufanelekileyo umgangatho wesondlo
Iipeptide ezincinci zenza ukulungelelaniswa kwamazinyo amaninzi kunye ne-ion zetsimbi ngokusebenzisa i-amino, i-carboxyl kunye namanye amaqela asebenzayo ukwenza isakhiwo se-ring chelate enamalungu amahlanu / amathandathu. Ukulungelelaniswa kweringi kunciphisa amandla enkqubo, isithintelo se-steric sikhusela ukuphazamiseka kwangaphandle, kunye nokungathathi hlangothi kwentlawulo kunciphisa ukunyanzeliswa kwe-electrostatic, ethi kunye ikhulise ukuzinza kwe-chelate.
| Ukuzinza kwee-ligands ezahlukeneyo ezibophelela kwii-ion zobhedu phantsi kweemeko ezifanayo ze-physiological | |
| Ligand Uzinzo rhoqo 1,2 | Ligand Uzinzo rhoqo 1,2 |
| Ilog10K[ML] | Ilog10K[ML] |
| IiAmino Acids | I-Tripeptide |
| IGlycine 8.20 | IGlycine-Glycine-Glycine 5.13 |
| Lysine 7.65 | IGlycine-Glycine-Histidine 7.55 |
| Methionine 7.85 | IGlycine Histidine Glycine 9.25 |
| I-Histidine 10.6 | IGlycine Histidine Lysine 16.44 |
| Aspartic acid 8.57 | I-Gly-Gly-Tyr 10.01 |
| Idipeptide | I-Tetrapeptide |
| IGlycine-Glycine 5.62 | Phenylalanine-Alanine-Alanine-Lysine 9.55 |
| IGlycine-Lysine 11.6 | I-Alanine-Glycine-Glycine-Histidine 8.43 |
| Tyrosine-Lysine 13.42 | I-Quote: 1.Uzinzo Constants Ukumisela kunye nokusetyenziswa, uPeter Gans. 2.Uzinzo olukhethwe ngokucokisekileyo lwezakhiwo zentsimbi,NIST Database 46. |
| I-Histidine-methionine 8.55 | |
| I-Alanine-Lysine 12.13 | |
| I-Histidine-serine 8.54 | |
Umzobo woku-1 Uzinzo oluzinzileyo lweeligands ezahlukeneyo ezibophelela kwiCu2+
Imithombo yeeminerali ebotshelelwe ngokubuthathaka inokwenzeka ukuba ifumane ukusabela kwe-redox kunye neevithamini, ioyile, i-enzymes kunye ne-antioxidants, echaphazela ixabiso elisebenzayo lezondlo zokutya. Nangona kunjalo, esi siphumo sinokuncitshiswa ngokukhetha ngononophelo i-trace element kunye nokuzinza okuphezulu kunye nokuphendula okuphantsi kunye namavithamini.
Ukuthatha iivithamini njengomzekelo, Concarr et al. (2021a) ufunde ukuzinza kwe-vitamin E emva kokugcinwa kwexesha elifutshane le-inorganic sulfate okanye iintlobo ezahlukeneyo ze-organic mineral premixes. Ababhali bafumanisa ukuba umthombo wezinto zokulandelela uthintele kakhulu ukuzinza kwe-vitamin E, kwaye i-premix isebenzisa i-organic glycinate ine-vitamin ephezulu yokulahleka kwe-31.9%, ilandelwa yi-premix isebenzisa i-amino acid complexes, eyayiyi-25.7%. Kwakungekho nantlukwano ebalulekileyo ekulahlekeni kokuzinza kwe-vitamin E kwi-premix equkethe i-protein salts xa kuthelekiswa neqela lokulawula.
Ngokufanayo, izinga lokugcinwa kwamavithamini kwi-organic trace element chelates ngendlela ye-peptides encinci (ebizwa ngokuba yi-x-peptide multi-minerals) iphezulu kakhulu kuneminye imithombo yamaminerali (Umfanekiso 2). (Qaphela: I-organic multi-minerals kwi-Figure 2 yi-glycine series multi-minerals).
Umzobo wesi-2 Isiphumo semixube evela kwimithombo eyahlukeneyo kwireyithi yokugcinwa kwevithamini
1) Ukunciphisa ungcoliseko kunye nokukhutshwa kwezinto ezikhutshwayo ukusombulula iingxaki zolawulo lokusingqongileyo
4. Iimfuno zomgangatho: umgangatho kunye nokuthotyelwa: ukubamba umgangatho ophezulu wokhuphiswano lwamazwe ngamazwe
1) Ukuziqhelanisa nemimiselo emitsha ye-EU: ukuhlangabezana neemfuno ze-2024 / EC imigaqo kunye nokubonelela ngeemephu zendlela ye-metabolic
2) Yenza izikhombisi ezinyanzelekileyo kunye nereyibhile ye-chelation rate, ukuhlukana rhoqo, kunye neeparitha zokuzinza kwamathumbu
I-3) Ukukhuthaza iteknoloji yokugcina ubungqina be-blockchain, iiparameters zenkqubo yokulayisha kunye neengxelo zovavanyo kuyo yonke inkqubo
Itekhnoloji encinci yokulandela itekhnoloji yepeptide ayisiyiyo nje inguqu kwizongezo zokutya, kodwa ikwayinjini engundoqo yenguqu eluhlaza kushishino lwemfuyo. Ngo-2025, ngokukhawuleziswa kwedijithali, isikali kunye nokuthengiswa kwamanye amazwe, obu buchwepheshe buza kubumba kwakhona ukhuphiswano lweshishini ngeendlela ezintathu "zokuphucula ukusebenza kakuhle-ukhuseleko lokusingqongileyo kunye nokunciphisa ukukhutshwa kwexabiso-kongeziweyo". Kwixesha elizayo, kuyimfuneko ukuqinisa ngakumbi intsebenziswano phakathi kwezoshishino, i-academia kunye nophando, ukukhuthaza ukuthengiswa kwemigangatho yezobugcisa, kunye nokwenza isisombululo saseTshayina sibe ngumqondiso wophuhliso oluzinzileyo lwemfuyo yehlabathi.
Uqhagamshelwano lwemidiya:
Elaine Xu
SUSTAR
Email: elaine@sustarfeed.com
Iselula / WhatsApp: +86 18880477902
Ixesha lokuposa: Apr-30-2025
